30 May 2022 to 2 June 2022
Asia/Dubai timezone

Optimisation and characterisation of a dual porosity medical grade porous medium for personalised inkjet printed dosages applications

1 Jun 2022, 11:15
15m
Oral Presentation (MS22) Manufactured Porous Materials for Industrial Applications MS22

Speaker

Hamed Aslannejad (| Stuttgart Center for Simulation Science (SIMTECH) | Stuttgart University, Germany and Porous Media Lab. | Universiteit Utrecht, the Netherlands )

Description

Personalized medicine enables tailored therapy, best response, and lowest side-effects to ensure better patient care. By means of inkjet printing technology, personalized medicine can be provided precisely, efficiently and affordably. In this work, we introduce a methodology based on inkjet printing which uses a porous substrate as career for Active Pharmaceutical ingredient (API). The porous substrate needs to have certain properties to uptake the API fast, distribute it uniformity, and realize it based on desired profile. To meet these criteria, a set of experiments has been designed and conducted. A list of required ingredients, granulation and tableting methodology have been identified to produce a Dual porosity porous tablet which fulfills required above-mentioned criteria as well as necessary mechanical strength before and after print. The pore network of the tablet was characterized to extract porosity, pore size distribution, connectivity, and permeability of the domain. Furthermore, the pore network of the tablet was extracted to be used in pore-scale two-phase flow simulation to study the movement of API inside the domain. The results of the model, yielded in appropriate printing process parameters.

Participation In person
Country Netherlands
MDPI Energies Student Poster Award No, do not submit my presenation for the student posters award.
Time Block Preference Time Block B (14:00-17:00 CET)
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Primary authors

Hamed Aslannejad (| Stuttgart Center for Simulation Science (SIMTECH) | Stuttgart University, Germany and Porous Media Lab. | Universiteit Utrecht, the Netherlands ) Mrs Tamanna Lashkari Mr Elmin Breejen Prof. Robbert Jan kok Rainer Helmig (University of Stuttgart) Prof. Oliver Röhrle (University of Stuttgart) S. Majid Hassanizadeh (Utrecht University)

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