Speaker
Description
Soft porous media often exhibit heterogeneous structures. For instance, biological tissues can be composed of multiple layers characterised by distinct mechanical and fluid-flow properties; similarly, in tissue engineering, multilayer scaffolds are known to promote cell survival and proliferation.
Under periodic loading—particularly common in these systems (e.g. due to cardiac pulsations, body motion, ...)—the physical implications of such heterogeneity on poromechanical couplings remain poorly understood.
Here, we address this gap by modelling a generic soft porous material composed of two layers with different material properties. To enable a controlled comparison and isolate the role of heterogeneity, we choose combinations of material properties (permeability, p-wave modulus, and porosity) resulting in a uniform poroelastic timescale T_{pe} in each layer. We show that, while T_{pe} is the key parameter governing the response of homogeneous materials, the same T_{pe} leads to markedly different distributions of strain, fluid flow, and solute transport in a heterogeneous system. These results provide insight into why layered structures may be more favourable for cell and tissue development than homogeneous ones.
| Country | France |
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