22–25 May 2023
Europe/London timezone

Porous biohybrid multifunctional membranes for biosensors and bioremediation

24 May 2023, 15:40
30m
Oral Presentation (MS24) Invited and Plenary Sessions

Speaker

Lidietta Giorno (Institute on Membrane Technology (CNR-ITM))

Description

Synthetic membranes are among the most effective technology in separation, fractionation, concentration, and purification. Their nanostructured pores have demonstrated their unique role also in implementing processes such as catalysis, and molecular recognition. Engineering the chemistry of the material, the structure of the pores, and the process conditions permits an extension of the areas of application of membranes. The combination of porous and mesoporous membranes with biomolecules leads to the development of artificial membranes with biofunctional properties. Biorecognition and bioconversion confined in micro and nanoscale compartments are emerging as important properties in the development of membrane-based biosensing and biocatalytic tools. For example, the trace presence of recalcitrant micropollutants (such as pesticides, antibiotics, hormones, etc.) in the environment causes chronic exposure that represents a threat to health and socio-economic wellness. The availability of technologies able to detect and eliminate trace micropollutants appears to be crucial.
The lecture will discuss the development of biofunctionalized porous membranes and their ability in intercepting traces of a model pesticide (such as paraoxon). The capability of membranes functionalized with an enzyme (phosphotriesterase) to fully degrade the pesticide will be also illustrated.
Superparamagnetic plasmonic nanoparticles (core-shell iron-gold nanoparticles) conjugated with enzymes are orderly arranged in porous polymeric frameworks able to accumulate the trace contaminant and enhance the interaction with the biochemical receptor. The role of membrane material, pore size, structure, morphology, topography, thickness, and surface energy on the mass transport, molecular interaction, and stabilization of the biomolecules will be outlined.

References

The authors would like to thank POR Calabria FESR-FSE 2014/2020 for the financial support to the SmartMatter project within the M-ERA.NET Call 2019.
National Research Council of Italy, Institute on Membrane Technology, CNR-ITM, Via P. Bucci, 17C, 87036 Rende (CS), Italy

Participation In-Person
Country Italy
MDPI Energies Student Poster Award No, do not submit my presenation for the student posters award.
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Primary authors

Lidietta Giorno (Institute on Membrane Technology (CNR-ITM)) Fabio Bazzarelli Rosalinda Mazzei Emma Piacentini Teresa Poerio Serena Regina Giuseppe Vitola

Presentation materials

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